pathway.svg 32 KB

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  40. <text id="text-line0" x="0" y="0em" dominant-baseline="central" text-anchor="middle">VLDL</text>
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  42. <g transform="translate(361.01851851851836 678.0092592592584)" font-weight="bold" id="text-for-f20" fill="#000000" font-size="12">
  43. <text id="text-line0" x="0" y="0em" dominant-baseline="central" text-anchor="middle">Tissues</text>
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  45. <g transform="translate(813.7037037037032 451.70634920634876)" font-weight="bold" id="text-for-fbb" fill="#000000" font-size="12">
  46. <text id="text-line0" x="0" y="0em" dominant-baseline="central" text-anchor="middle">Plasma</text>
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  48. <g transform="translate(377.19047619047655 383.3333333333333)" font-weight="bold" id="text-for-c83" fill="#000000" font-size="12">
  49. <text id="text-line0" x="0" y="0em" dominant-baseline="central" text-anchor="middle">IDL</text>
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  51. <g transform="translate(186.66666666666666 383.3333333333333)" font-weight="bold" id="text-for-d57" fill="#000000" font-size="12">
  52. <text id="text-line0" x="0" y="0em" dominant-baseline="central" text-anchor="middle">LDL</text>
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  54. <g transform="translate(479.5238095238097 484.76190476190493)" font-weight="bold" id="text-for-cdf" fill="#000000" font-size="12">
  55. <text id="text-line0" x="0" y="0em" dominant-baseline="central" text-anchor="middle">HDL</text>
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  57. <g transform="translate(848.0952380952393 68.09523809523814)" font-weight="bold" id="text-for-e46" fill="#000000" font-size="10">
  58. <text id="text-line0" x="0" y="0em" dominant-baseline="central" text-anchor="middle">Cell Membrane</text>
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  60. <g transform="translate(552.3160678994171 124.72359141038902)" id="text-for-fa9" font-weight="bold" fill="#000000" font-size="12">
  61. <text id="text-line0" x="0" y="0em" dominant-baseline="central" text-anchor="middle">Free FA</text>
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  64. <text id="text-line0" x="0" y="0em" dominant-baseline="central" text-anchor="middle">Phospholipid</text>
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  66. <g transform="translate(756.6666666666666 212.33333333333334)" id="text-for-c66" font-weight="bold" fill="#000000" font-size="12">
  67. <text id="text-line0" x="0" y="0em" dominant-baseline="central" text-anchor="middle">Triglycerides</text>
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  69. <g transform="translate(856.6666666666666 320)" font-weight="bold" id="text-for-b93" fill="#000000" font-size="12">
  70. <text id="text-line0" x="0" y="0em" dominant-baseline="central" text-anchor="middle">Liver cell</text>
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  72. <g transform="translate(739.9999999999987 419.9999999999998)" id="text-for-f90e3" fill-opacity="0.1" font-weight="bold" fill="#808080" font-size="1">
  73. <text id="text-line0" x="0" y="0em" dominant-baseline="central" text-anchor="middle">Group object</text>
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  76. <g transform="translate(562.809523809524 491.1904761904762)" id="text-for-c4e" fill="#000000" font-size="10">
  77. <text id="text-line0" x="0" y="0em" dominant-baseline="central" text-anchor="middle">Pltp</text>
  78. </g>
  79. <path d="M57.57717750826917,153.9873208379272L138.5771775082692,153.9873208379272L138.5771775082692,174.9873208379272L57.57717750826917,174.9873208379272Z" fill="#ffffff" id="e4e59" stroke-width="1" stroke="#ff0033" class="has-xref"></path>
  80. <g transform="translate(98.07717750826917 164.4873208379272)" id="text-for-e4e59" font-weight="bold" fill="#ff0033" font-size="10">
  81. <text id="text-line0" x="0" y="0em" dominant-baseline="central" text-anchor="middle">Statin</text>
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  85. <text id="text-line0" x="0" y="0em" dominant-baseline="central" text-anchor="middle">Cholesterol</text>
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  88. <g transform="translate(347 236)" id="text-for-ba3f8" fill="#0000ff" font-size="10">
  89. <text id="text-line0" x="0" y="0em" dominant-baseline="central" text-anchor="middle">Cholesterol</text>
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  92. <g transform="translate(98.07717750826919 236)" id="text-for-f6a60" fill="#0000ff" font-size="10">
  93. <text id="text-line0" x="0" y="0em" dominant-baseline="central" text-anchor="middle">Acetyl-CoA</text>
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  96. <g transform="translate(346 108)" id="text-for-ecd6d" fill="#0000ff" font-size="10">
  97. <text id="text-line0" x="0" y="0em" dominant-baseline="central" text-anchor="middle">Cholic acid</text>
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  101. <text id="text-line0" x="0" y="0em" dominant-baseline="central" text-anchor="middle">Scarb1</text>
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  104. <g transform="translate(739.9999999999987 389.9999999999998)" id="text-for-a5e" fill="#000000" font-size="10">
  105. <text id="text-line0" x="0" y="0em" dominant-baseline="central" text-anchor="middle">Apoc3</text>
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  108. <g transform="translate(739.9999999999987 449.9999999999998)" id="text-for-a64" fill="#000000" font-size="10">
  109. <text id="text-line0" x="0" y="0em" dominant-baseline="central" text-anchor="middle">Apoc2</text>
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  112. <g transform="translate(739.9999999999987 429.9999999999998)" id="text-for-fad" fill="#000000" font-size="10">
  113. <text id="text-line0" x="0" y="0em" dominant-baseline="central" text-anchor="middle">Apoe</text>
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  115. <path d="M709.4999999999987,399.4999999999998L770.4999999999987,399.4999999999998L770.4999999999987,420.4999999999998L709.4999999999987,420.4999999999998Z" fill="#ffffff" id="f9d" stroke-width="1" stroke="#000000" class="has-xref"></path>
  116. <g transform="translate(739.9999999999987 409.9999999999998)" id="text-for-f9d" fill="#000000" font-size="10">
  117. <text id="text-line0" x="0" y="0em" dominant-baseline="central" text-anchor="middle">Apoc1</text>
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  120. <g transform="translate(580.4761904761907 569.047619047619)" id="text-for-b95" fill="#000000" font-size="10">
  121. <text id="text-line0" x="0" y="0em" dominant-baseline="central" text-anchor="middle">Apoa4</text>
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  123. <path d="M475.261904761905,558.547619047619L536.261904761905,558.547619047619L536.261904761905,579.547619047619L475.261904761905,579.547619047619Z" fill="#ffffff" id="e58" stroke-width="1" stroke="#000000" class="has-xref"></path>
  124. <g transform="translate(505.761904761905 569.047619047619)" id="text-for-e58" fill="#000000" font-size="10">
  125. <text id="text-line0" x="0" y="0em" dominant-baseline="central" text-anchor="middle">Apoa1</text>
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  127. <path d="M521.5,225.50000000000003L646.5,225.50000000000003L646.5,246.50000000000003L521.5,246.50000000000003Z" fill="#ffffff" id="a24b2" stroke-width="1" stroke="#0000ff" class="has-xref"></path>
  128. <g transform="translate(584 236.00000000000003)" id="text-for-a24b2" fill="#0000ff" font-size="10">
  129. <text id="text-line0" x="0" y="0em" dominant-baseline="central" text-anchor="middle">Cholesterol Ester</text>
  130. </g>
  131. <path d="M336.6904761904764,560.5000000000001L397.6904761904764,560.5000000000001L397.6904761904764,581.5000000000001L336.6904761904764,581.5000000000001Z" fill="#ffffff" id="d75" stroke-width="1" stroke="#000000" class="has-xref"></path>
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  133. <text id="text-line0" x="0" y="0em" dominant-baseline="central" text-anchor="middle">Abca1</text>
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  135. <path d="M346.6904761904765,479.1190476190473L407.6904761904765,479.1190476190473L407.6904761904765,500.1190476190473L346.6904761904765,500.1190476190473Z" fill="#ffffff" id="f82" stroke-width="1" stroke="#000000" class="has-xref"></path>
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  137. <text id="text-line0" x="0" y="0em" dominant-baseline="central" text-anchor="middle">Lcat</text>
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  144. <g transform="translate(255.5238095238094 419.57142857142884)" id="text-for-af7" fill="#000000" font-size="10">
  145. <text id="text-line0" x="0" y="0em" dominant-baseline="central" text-anchor="middle">Lipc</text>
  146. </g>
  147. <path d="M443.8333333333335,407.16666666666697L504.8333333333335,407.16666666666697L504.8333333333335,428.16666666666697L443.8333333333335,428.16666666666697Z" fill="#ffffff" id="c3e" stroke-width="1" stroke="#000000" class="has-xref"></path>
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  149. <text id="text-line0" x="0" y="0em" dominant-baseline="central" text-anchor="middle">Lpl</text>
  150. </g>
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  153. <text id="text-line0" x="0" y="0em" dominant-baseline="central" text-anchor="middle">Lrp1</text>
  154. </g>
  155. <path d="M201.16666666666666,319.8333333333333L262.16666666666663,319.8333333333333L262.16666666666663,340.8333333333333L201.16666666666666,340.8333333333333Z" fill="#ffffff" id="d72" stroke-width="1" stroke="#000000" class="has-xref"></path>
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  157. <text id="text-line0" x="0" y="0em" dominant-baseline="central" text-anchor="middle">Ldlr</text>
  158. </g>
  159. <path d="M643.876506134835,112.23746377756173L704.876506134835,112.23746377756173L704.876506134835,133.23746377756174L643.876506134835,133.23746377756174Z" fill="#ffffff" id="be0" stroke-width="1" stroke="#000000" class="has-xref"></path>
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  172. <g transform="translate(416.6666666666667 164.4873208379272)" id="text-for-da7" fill="#000000" font-size="10">
  173. <text id="text-line0" x="0" y="0em" dominant-baseline="central" text-anchor="middle">Cyp7a1</text>
  174. </g>
  175. <path d="M174.83333333333334,153.9873208379272L235.83333333333334,153.9873208379272L235.83333333333334,174.9873208379272L174.83333333333334,174.9873208379272Z" fill="#ffffff" id="e04" stroke-width="1" stroke="#000000" class="has-xref"></path>
  176. <g transform="translate(205.33333333333334 164.4873208379272)" id="text-for-e04" fill="#000000" font-size="10">
  177. <text id="text-line0" x="0" y="0em" dominant-baseline="central" text-anchor="middle">Hmgcr</text>
  178. </g>
  179. <g id="info-box-0" class="text-area info-box">
  180. <text id="info-box-text0" class="item" x="0" y="14">
  181. <tspan class="info-box-item-property-name">Title:</tspan>
  182. <tspan class="info-box-item-property-value">Statin Pathway</tspan>
  183. </text>
  184. <text id="info-box-text1" class="item" x="0" y="28">
  185. <tspan class="info-box-item-property-name">Organism:</tspan>
  186. <tspan class="info-box-item-property-value">Mus musculus</tspan>
  187. </text>
  188. </g>
  189. <text class="citation" transform="translate(0 0)"></text>
  190. <text class="citation" transform="translate(0 0)"></text>
  191. <text class="citation" transform="translate(0 0)"></text>
  192. <text class="citation" transform="translate(0 0)"></text>
  193. <text class="citation" transform="translate(0 0)"></text>
  194. <text class="citation" transform="translate(0 0)"></text>
  195. <text class="citation" transform="translate(0 0)"></text>
  196. <text class="citation" transform="translate(0 0)"></text>
  197. <text class="citation" transform="translate(0 0)"></text>
  198. <text class="citation" transform="translate(0 0)"></text>
  199. <text class="citation" transform="translate(0 0)"></text>
  200. <text class="citation" transform="translate(0 0)"></text>
  201. <text class="citation" transform="translate(0 0)"></text>
  202. <text class="citation" transform="translate(0 0)"></text>
  203. <text class="citation" transform="translate(0 0)"></text>
  204. <text class="citation" transform="translate(0 0)"></text>
  205. <text class="citation" transform="translate(0 0)"></text>
  206. <text class="citation" transform="translate(0 0)"></text>
  207. <text class="citation" transform="translate(0 0)"></text>
  208. <text class="citation" transform="translate(0 0)"></text>
  209. <text class="citation" transform="translate(0 0)"></text>
  210. <text class="citation" transform="translate(0 0)"></text>
  211. <text class="citation" transform="translate(0 0)"></text>
  212. <text class="citation" transform="translate(0 0)"></text>
  213. <text class="citation" transform="translate(0 0)"></text>
  214. <text class="citation" transform="translate(0 0)"></text>
  215. <text class="citation" transform="translate(0 0)"></text>
  216. <text class="citation" transform="translate(0 0)"></text>
  217. <defs>
  218. <style type="text/css">
  219. svg {
  220. color-interpolation: auto;
  221. image-rendering: auto;
  222. shape-rendering: auto;
  223. vector-effect: non-scaling-stroke;
  224. background: white;
  225. /* removed fill and stroke since they override marker specs */
  226. /* fill: white;
  227. stroke: black; */
  228. }
  229. /* default color for pathway elements */
  230. .default-fill-color {
  231. fill: black;
  232. }
  233. .default-stroke-color {
  234. stroke: black;
  235. }
  236. /* default color of the background drawing board */
  237. .board-fill-color {
  238. fill: white;
  239. }
  240. .board-stroke-color {
  241. stroke: white;
  242. }
  243. .text-area {
  244. font-family: Sans-Serif, Helvetica, Arial;
  245. text-align: center;
  246. vertical-align: middle;
  247. font-size: 10px;
  248. fill: black;
  249. fill-opacity: 1;
  250. stroke: none;
  251. }
  252. .citation {
  253. font-family: Sans-Serif, Helvetica, Arial;
  254. text-align: center;
  255. vertical-align: top;
  256. font-size: 7px;
  257. fill: #999999;
  258. fill-opacity: 1;
  259. stroke: none;
  260. }
  261. .info-box {
  262. font-family: Sans-Serif;
  263. font-size: 10px;
  264. fill: black;
  265. stroke: none;
  266. text-align: left;
  267. vertical-align: top;
  268. }
  269. .info-box-item-property-name {
  270. font-weight: bold;
  271. }
  272. .info-box-item-property-value {} .data-node {
  273. text-align: right;
  274. fill-opacity: 1;
  275. fill: white;
  276. stroke: black;
  277. stroke-width: 1;
  278. stroke-dasharray: 0;
  279. stroke-miterlimit: 1;
  280. pointer-events: auto;
  281. }
  282. .data-node: hover {
  283. cursor: pointer;
  284. }
  285. .has-xref: hover {
  286. cursor: pointer;
  287. }
  288. .data-node.gene-product {} .metabolite {
  289. stroke: blue;
  290. }
  291. .data-node.metabolite &gt;
  292. .text-area {
  293. fill: blue;
  294. fill-opacity: 1;
  295. stroke: none;
  296. }
  297. .data-node.pathway {
  298. stroke: none;
  299. fill-opacity: 0;
  300. }
  301. .data-node.pathway &gt;
  302. .text-area {
  303. fill: rgb(20, 150, 30);
  304. fill-opacity: 1;
  305. font-size: 12px;
  306. font-weight: bold;
  307. }
  308. .data-node.protein {} .data-node.rna {} .data-node.unknown {} .label {
  309. stroke: null;
  310. stroke-width: 0;
  311. fill-opacity: 0;
  312. stroke-dasharray: 0;
  313. stroke-miterlimit: 1;
  314. }
  315. .shape {
  316. fill-opacity: 0;
  317. stroke: black;
  318. stroke-dasharray: 0;
  319. stroke-miterlimit: 1;
  320. }
  321. .shape.none {
  322. fill: none;
  323. fill-opacity: 0;
  324. stroke: none;
  325. }
  326. g.group-node &gt;
  327. .shape {
  328. fill-opacity: 0.098;
  329. stroke: gray;
  330. stroke-miterlimit: 1;
  331. stroke-width: 1px;
  332. pointer-events: none;
  333. }
  334. .group-node {
  335. fill-opacity: 0.098;
  336. stroke: gray;
  337. stroke-miterlimit: 1;
  338. stroke-width: 1px;
  339. pointer-events: none;
  340. }
  341. .group-node &gt;
  342. .text-area {
  343. fill-opacity: 0.4;
  344. font-family: Serif, Times;
  345. font-size: 32px;
  346. fill: black;
  347. stroke-width: 0;
  348. font-weight: bold;
  349. }
  350. .group-node.none {
  351. fill: rgb(180, 180, 100);
  352. stroke-dasharray: 5, 3;
  353. }
  354. .group-node.none &gt;
  355. .text-area {
  356. display: none;
  357. }
  358. /*.group-node.none:hover {
  359. fill: rgb(255,180,100);
  360. fill-opacity: 0.05;
  361. }*/
  362. .group-node.group {
  363. fill-opacity: 0;
  364. stroke: none;
  365. }
  366. .group-node.group &gt;
  367. .text-area {
  368. display: none;
  369. }
  370. /*.group-node.group:hover {
  371. fill: rgb(0,0,255);
  372. stroke-width: 1px;
  373. stroke-dasharray: 5,3;
  374. stroke: gray;
  375. fill-opacity: 0.1;
  376. }*/
  377. .group-node.complex {
  378. fill: rgb(180, 180, 100);
  379. }
  380. .group-node.complex &gt;
  381. .text-area {
  382. display: none;
  383. }
  384. /*.group-node.complex:hover {
  385. fill: rgb(255,0,0);
  386. fill-opacity: 0.05;
  387. }*/
  388. .group-node.pathway {
  389. fill: rgb(0, 255, 0);
  390. stroke-dasharray: 5, 3;
  391. }
  392. /*.group-node.pathway:hover {
  393. fill: rgb(0,255,0);
  394. fill-opacity: 0.2;
  395. }*/
  396. .group-node.pathway &gt;
  397. .text-area {
  398. fill: rgb(20, 150, 30);
  399. stroke: rgb(20, 150, 30);
  400. }
  401. .cellular-component {
  402. fill-opacity: 0;
  403. stroke: silver;
  404. }
  405. .graphical-line {
  406. fill: none;
  407. stroke: black;
  408. stroke-width: 1px;
  409. }
  410. .interaction {
  411. fill: none;
  412. stroke: black;
  413. stroke-width: 1px;
  414. }
  415. marker {
  416. /* this is what should work per the spec
  417. stroke-dasharray: none; */
  418. /* but I need to add this to make it work in Safari */
  419. stroke-dasharray: 9999999999999999999999999;
  420. }
  421. .marker-end {
  422. -webkit-transform: rotate(180deg);
  423. -webkit-transform-origin: 50% 50%;
  424. -o-transform: rotate(180deg);
  425. -o-transform-origin: 50% 50%;
  426. transform: rotate(180deg);
  427. transform-origin: 50% 50%;
  428. }
  429. .solid-stroke {
  430. /* this is what should work per the spec
  431. stroke-dasharray: none; */
  432. /* but I need to add this to make it work in Safari */
  433. stroke-dasharray: 9999999999999999999999999;
  434. }
  435. .dashed-stroke {
  436. stroke-dasharray: 5, 3;
  437. }
  438. </style>
  439. <marker id="id-arrow-end-000000" orient="auto" markerUnits="strokeWidth" preserveAspectRatio="none" refY="6" viewBox="0 0 12 12" markerWidth="12" markerHeight="12" refX="12">
  440. <g id="g-id-arrow-end-000000" transform="rotate(180, 6, 6)">
  441. <rect x="0" y="5.4" width="2" height="1.2" stroke="white" fill="white"></rect>
  442. <polygon points="12,11 0,6 12,1" stroke-width="0" fill="#000000"></polygon>
  443. </g>
  444. </marker>
  445. <marker id="id-arrow-start-000000" orient="auto" markerUnits="strokeWidth" preserveAspectRatio="none" refY="6" viewBox="0 0 12 12" markerWidth="12" markerHeight="12" refX="0">
  446. <g id="g-id-arrow-start-000000">
  447. <rect x="0" y="5.4" width="2" height="1.2" stroke="white" fill="white"></rect>
  448. <polygon points="12,11 0,6 12,1" stroke-width="0" fill="#000000"></polygon>
  449. </g>
  450. </marker>
  451. <marker id="id-tbar-end-ff0000" orient="auto" markerUnits="strokeWidth" preserveAspectRatio="none" refY="10" viewBox="0 0 10 20" markerWidth="10" markerHeight="20" refX="10">
  452. <g id="g-id-tbar-end-ff0000" transform="rotate(180, 5, 10)">
  453. <rect x="0" y="9" width="8" height="2" fill="white"></rect>
  454. <line x="0" y="0" width="12" height="12" stroke="#ff0000" stroke-width="1.8" x1="7" y1="0" x2="7" y2="20"></line>
  455. </g>
  456. </marker>
  457. <style type="text/css">
  458. .svg-pan-zoom-control {
  459. cursor: pointer;
  460. fill: black;
  461. fill-opacity: 0.333;
  462. }
  463. .svg-pan-zoom-control: hover {
  464. fill-opacity: 0.8;
  465. }
  466. .svg-pan-zoom-control-background {
  467. fill: white;
  468. fill-opacity: 0.5;
  469. }
  470. .svg-pan-zoom-control-background {
  471. fill-opacity: 0.8;
  472. }
  473. </style>
  474. </defs>
  475. </g>
  476. </svg>